KAT2 Antibody

Code CSB-PA655727XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) KAT2 Polyclonal antibody
Uniprot No.
Target Names
KAT2
Alternative Names
KAT2; At4g18290; T9A21.140; Potassium channel KAT2
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana KAT2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Highly selective inward-rectifying potassium channel. This voltage-dependent channel could mediate long-term potassium influx into guard cells leading to stomatal opening. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by hyperpolarization. The channel activity is enhanced upon external acidification.
Gene References into Functions
  1. The Arabidopsis K(+) channel KAT1 complements in K(+)-limited medium the growth of the K(+) uptake defective Saccharomyces cerevisiae mutant strain CY162, while another K(+) channel, AKT2, does not. PMID: 28933647
  2. CPK13 reduces stomatal aperture through its inhibition of the guard cell-expressed KAT2 and KAT1 channels. PMID: 25037208
  3. The nine-amino acid stretch 312TVRAASEFA320 that composes the first C-linker alpha-helix located just below the pore is a crucial determinant of KAT2 channel activity. PMID: 24406792
  4. KAT2 contributes to the synthesis of substituted hydroxybenzoylcholines.KAT2 plays the primary role in benzoic acid synthesis. PMID: 24254312
  5. KAT2 was able to re-locate AtKC1 fused to GFP from endomembranes to the plasma membrane, indicating that heteromeric AtKC1-KAT2 channels are efficiently targeted to the plasma membrane. PMID: 21518051
  6. KAT2 may function downstream of an important WRKY transcription repressor WRKY40, which may link KAT2 with the ABA receptor ABAR/CHLH-mediated signaling. PMID: 21257607

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Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Potassium channel family, Plant (TC 1.A.1.4) subfamily
Tissue Specificity
Expressed in guard cells of hypocotyls, stems leaves and petioles. Detected also in the phloem of minor veins and in flower at a lower level.
Database Links

KEGG: ath:AT4G18290

STRING: 3702.AT4G18290.1

UniGene: At.431

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