ken Antibody

Datasheet

Code	CSB-PA525658XA01DLU
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Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) ken Polyclonal antibody

Uniprot No.

O77459

Target Names

ken

Alternative Names

ken antibody; CG5575Transcription factor Ken antibody; Protein Ken and Barbie antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) ken protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Transcription factor required for terminalia development. Negative regulator of the JAK/STAT pathway: represses JAK/STAT-dependent expression of ventral veins lacking (vvl) in the posterior spiracles.

Gene References into Functions

In ken/barbie male flies lacking external genitalia, courtship and physical contact without ejaculation was unable to replicate the mating effect. PMID: 28851647
Data show that that BCL6 homolog ken and barbie (Ken) has an important role in the inhibition of somatic cyst stem cells (CySCs) differentiation. PMID: 22580161
Ken is a novel regulator of JAK/STAT signaling whose dynamic spatial and temporal expression is capable of selectively modulating the transcriptional repertoire elicited by activated STAT92E in vivo. PMID: 16401426
Ken and barbie mutants have defects in escape behaviour, behavioural responses to visual stimuli and synaptic functions in the giant fibre system. PMID: 16879616

Subcellular Location

Nucleus.

Tissue Specificity

Expressed from stage 5 in two rather faint stripes at positions of 64% (anterior domain; AD) and 17% (posterior domain; PD) egg length. During early gastrulation, at stage 6, these two stripes become more evident and detectable at the region posterior to

Database Links

KEGG: dme:Dmel_CG5575

STRING: 7227.FBpp0072038

UniGene: Dm.2792

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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ken Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background