MKK3 Antibody

Code CSB-PA900212XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MKK3 Polyclonal antibody
Uniprot No.
Target Names
MKK3
Alternative Names
MKK3 antibody; At5g40440 antibody; MPO12.19 antibody; MPO12_150 antibody; Mitogen-activated protein kinase kinase 3 antibody; AtMKK3 antibody; MAP kinase kinase 3 antibody; EC 2.7.12.2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana MKK3 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
MKK3-MPK6 module plays an important role in the jasmonate signal transduction pathway through the negative regulation of MYC2/JIN1 expression. Activates by phosphorylation the downstream MPK6, MPK7 and MPK8. MKK3-MPK7 module acts as a positive regulator of PR1 gene expression. MKK3-MPK8 module negatively regulates ROS accumulation through controlling expression of the RBOHD gene. Component of the abscisic acid (ABA) signaling pathway that may act as ABA signal transducer in the context of abiotic stresses. Activator of the C group MAP kinases. Activates MPK7 in response to ABA. Mitogen-activated protein kinase (MAPK) that is specifically regulated by MAPKKK20 and mediates signaling that regulates cortical microtubule functions.
Gene References into Functions
  1. This study suggests that MKK3 acts in negative regulation in darkness and in light-induced MAPK activation during dark-light transition. PMID: 26082029
  2. MAPK KINASE 3 (MKK3)-MAPK 6 (MPK6) unit plays a key role in jasmonic acid-dependent negative regulation of ATMYC2/JIN1 expression.[MKK3] PMID: 17369371
  3. Results reveal that the MKK3 pathway plays a role in pathogen defense and further underscore the importance and complexity of MAPK signaling in plant stress responses. PMID: 17933903
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily
Tissue Specificity
Mostly expressed in leaves, and, to a lower extent, in roots, seedlings, flower buds, flowers and siliques.
Database Links

KEGG: ath:AT5G40440

STRING: 3702.AT5G40440.1

UniGene: At.350

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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