mex-5 Antibody

Datasheet

Code	CSB-PA895023XA01CXY
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Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans mex-5 Polyclonal antibody

Uniprot No.

Q9XUB2

Target Names

mex-5

Alternative Names

mex-5 antibody; W02A2.7Zinc finger protein mex-5 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans mex-5 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Functions with mex-6 to affect embryonic viability, establish soma germline asymmetry in embryos and establish plk-1, pie-1, mex-1, and pos-1 asymmetry in embryos. Also affects formation of intestinal cells. Binds to mRNA in vitro, and inhibits pgl-3-mediated P-granule formation, probably by competing with pgl-3 for binding to mRNA.

Gene References into Functions

Antagonistic activities of PAR-1 and PP2A regulate MEX-5 diffusion to establish the MEX-5 protein gradient along the anterior-to-posterior axis of the one-cell C. elegans embryo. PMID: 21925318
asymmetric cortically localized PAR proteins mediate the anterior enrichment of MEX-5 by reversibly changing its diffusion rate at spatially distinct points in the embryo PMID: 20627961
analysis of RNA recognition by the embryonic polarity determinant MEX-5 PMID: 17264081
vivo. PAR-1 and PAR-4 kinase activities are required for the phosphorylation of S458, providing a link between PAR polarity proteins and the cytoplasmic asymmetry of MEX-5 PMID: 18842813

Subcellular Location

Cytoplasm.

Tissue Specificity

Asymmetrically localized to the anterior of the zygote before mitotic division, then differentially distributed to the somatic blastomere precursor cells.

Database Links

KEGG: cel:CELE_W02A2.7

STRING: 6239.W02A2.7.2

UniGene: Cel.23008

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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mex-5 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background