MGM101 Antibody

Code CSB-PA329199XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MGM101 Polyclonal antibody
Uniprot No.
Target Names
MGM101
Alternative Names
MGM101 antibody; MGM9 antibody; YJR144W antibody; J2181Mitochondrial genome maintenance protein MGM101 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MGM101 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Performs an essential function in the repair of oxidatively damaged mtDNA that is required for the maintenance of the mitochondrial genome. Binds to DNA.
Gene References into Functions
  1. The carboxy terminal-tail of Mgm101, likely displayed on the ring surface, is required for single stranded DNA binding. PMID: 23536705
  2. Data indicate that Mgm101p is found in the mitochondrial nucleoid along with enzymes and proteins involved in mtDNA replication. PMID: 23418572
  3. A potential role of Cys-216 and Cys-217 in regulating Mgm101 function and the repair of damaged mtDNA under stress conditions. PMID: 22948312
  4. Mgm101 is a Rad52-related protein required for mitochondrial DNA recombination PMID: 22027892
  5. a previously identified recessive temperature-sensitive mgm101-1ts mutation was used as a detection system to examine the functionality of Mgm101p PMID: 17311591

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Subcellular Location
Mitochondrion matrix, mitochondrion nucleoid.
Protein Families
MGM101 family
Database Links

KEGG: sce:YJR144W

STRING: 4932.YJR144W

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