mmi1 Antibody

1. The authors propose that Mmi1 recruits the Ccr4-Not complex to counteract its own inhibitor Mei2, thereby locking the system in a stable state that ensures the repression of the meiotic program by Mmi1. PMID: 28841135
2. Mmi1 can recognize and bind a class of meiosis-specific transcripts expressed inappropriately in mitotic cells; structural insights into the specific recognition of these mRNAs by the YTH domain containing protein Mmi1 have been presented. PMID: 28735863
3. report the 1.75 A crystal structure of the Mmi1 YTH domain and provide evidence that Mmi1 recognizes DSR RNA via a binding mode distinct from that of structurally homologous YTH proteins that recognize m(6)A-modified RNA PMID: 27165520
4. Erh1 and the RNA-binding protein Mmi1 form a stoichiometric complex, called the Erh1-Mmi1 complex (EMC), to promote meiotic mRNA decay and facultative heterochromatin assembly. PMID: 26942678
5. Mmi1 YTH domain selectively recognizes the determinant of selective removal RNA motif. PMID: 26673708
6. Mmi1 can specifically regulate the splicing of particular introns in a transcript: it inhibits the splicing of introns that are in the vicinity of putative Mmi1 binding sites, while allowing the splicing of other introns that are far from such sites. PMID: 22046364
7. Mei2 tethers Mmi1 and thereby stabilizes the transcripts necessary for the progression of meiosis PMID: 20948174

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KEGG: spo:SPCC736.12c

STRING: 4896.SPCC736.12c.1