mof Antibody

1. Accumulation of Mof at the Diap1 promoter 800 bp upstream of the transcription start site in wild type larvae is significantly higher (up to two folds) compared to mof1 mutants. PMID: 26711898
2. MOF controls Checkpoint protein2 and regulates genomic stability during early embryogenesis. PMID: 23347679
3. The role of MOF in the response to ionizing radiation is conserved between Drosophila and mammals. PMID: 22072291
4. It was shown that the MOF chromobarrel domain is essential for H4K16 acetylation throughout the Drosophila genome and is required for spreading of the male-specific lethal complex on the X chromosome. PMID: 22421046
5. The activation potential of MOF is constrained in male cells in the context of the DCC to arrive at the 2-fold activation of transcription characteristic of dosage compensation. PMID: 20620953
6. The roX1 and roX2 genes produce redundant, male-specific lethal transcripts required for targeting the MSL complex. PMID: 11867536
7. chromo barrel domain structure from the MOF acetyltransferase PMID: 15964847
8. We purify enzymatically active MSL complexes from Drosophila embryos. We find a stable association of the histone H4 lysine 16-specific acetyltransferase MOF with the RNA/protein containing MSL complex as well as with an evolutionary conserved complex. PMID: 16543150
9. Data show that the non-dosage compensated Lsp1alpha gene of Drosophila melanogaster escapes acetylation by MOF in larval fat body nuclei, but is flanked by two dosage compensated genes. PMID: 17511883
10. MOF is an essential factor for embryogenesis and oncogenesis PMID: 17967868
11. MOF is not only involved in the onset of dosage compensation, but also acts as a regulator of gene expression in the Drosophila genome. PMID: 18510926

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KEGG: dme:Dmel_CG3025

STRING: 7227.FBpp0070794

UniGene: Dm.2952