Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MYC2 Polyclonal antibody

Uniprot No.

Q39204

Target Names

MYC2

Alternative Names

MYC2 antibody; BHLH6 antibody; EN38 antibody; JAI1 antibody; JIN1 antibody; RAP1 antibody; RD22BP1 antibody; ZBF1 antibody; At1g32640 antibody; F6N18.4 antibody; Transcription factor MYC2 antibody; AtMYC2 antibody; Basic helix-loop-helix protein 6 antibody; AtbHLH6 antibody; bHLH 6 antibody; Protein JASMONATE INSENSITIVE 1 antibody; R-homologous Arabidopsis protein 1 antibody; RAP-1 antibody; Transcription factor EN 38 antibody; Z-box binding factor 1 protein antibody; bHLH transcription factor bHLH006 antibody; rd22BP1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana MYC2 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Target Background

Function

Transcriptional activator. Common transcription factor of light, abscisic acid (ABA), and jasmonic acid (JA) signaling pathways. With MYC3 and MYC4, controls additively subsets of JA-dependent responses. In cooperation with MYB2 is involved in the regulation of ABA-inducible genes under drought stress conditions. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the MYC recognition site (5'-CACATG-3'), and to the G-box (5'-CACNTG-3') and Z-box (5'-ATACGTGT-3') of promoters. Binds directly to the promoters of the transcription factors PLETHORA1 (PLT1) and PLT2 and represses their expression. Negative regulator of blue light-mediated photomorphogenic growth and blue- and far-red-light regulated gene expression. Activates multiple TIFY/JAZ promoters. Positive regulator of lateral root formation. Regulates sesquiterpene biosynthesis. Subjected to proteasome-dependent proteolysis. The presence of the destruction element (DE) involved in turnover is required for the function to regulate gene transcription.

Gene References into Functions

the 2.7 A crystal structure of the MYC2 bHLH domain complexed with G-box DNA, showing a cis-tetrameric structure, is reported. PMID: 28514654
allantoin can activate the MYC2-regulated jasmonic acid signaling pathway through abscissic acid production. PMID: 26931169
MYC2 interacts with ANAC019 to co-regulate the expression of NYE1 during jasmonic acid-induced chlorophyll degradation. PMID: 26407000
Under salt stress, JA almost did not render a positive effect on the jin1 plants. It is concluded that the protein JIN1/MYC2 is involved in control of protective systems under salt stress. PMID: 27266252
MYC2 is targeted by PUB10 for degradation during jasmonic acid responses. PMID: 26163577
MYC2 differentially regulates GATA-box conaining promoters during seedling development in Arabidopsis PMID: 23857363
Together, these results reveal that phosphorylation-coupled turnover of MYC2 stimulates its transcription activity. PMID: 23593022
MYC2 regulates RGL3 expression through a direct association with its promotor. PMID: 22892320
During jasmonate signaling, MED25 physically associates with the basic helix-loop-helix transcription factor MYC2 in promoter regions of MYC2 target genes and exerts a positive effect on MYC2-regulated gene transcription. PMID: 22822206
MYC2 interacts with RGA proteinsin regulating sesquiterpene synthase gene expression PMID: 22669881
jasmonic acid predominantly promotes MYC2 protein accumulation in the morning and TIME FOR COFFEE represses accumulation of the MYC2 PMID: 22693280
MYC2 acts as a negative regulator of light induced gene expression. PMID: 22424472
MYC2-mediated repression of PLT expression is involved in jasmonate inhibition of primary root growth. PMID: 21954460
The jasmonate-responsive activity of the jasmonate-responsive element from the ORCA3 promoter interacts in vitro and in vivo with the basic helix-loop-helix transcription factor AtMYC2. PMID: 21306988
High- and medium-affinity binding sites are over-represented in promoters of MYC2- or ERF1 (ethylene-responsive transcription factor 1B)-regulated genes, and therefore they may represent new cis-regulatory elements. PMID: 21284757
The role of jasmonate and salicylic acid signaling in susceptibility to P. syringae infection in A. thaliana mutants is reported. PMID: 16838791
These results provide new insights into the function of MYC2 and the transcriptional coordination of the jasmonic acid signaling pathway. PMID: 17616737
results pinpoint MYC2 as a potential regulator in priming for enhanced JA-responsive gene expression during rhizobacteria-mediated ISR PMID: 18657213

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Subcellular Location

Nucleus.

Tissue Specificity

Widely expressed in the whole plant with the highest expression in stem. Constitutively expressed in dark- and light-grown seedlings.

Database Links

KEGG: ath:AT1G32640

STRING: 3702.AT1G32640.1

UniGene: At.22648

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MYC2 Antibody

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