Mt3 Antibody

1. the absence of Mt3 reduces Abeta uptake in astrocytes through an abnormality in actin polymerization. PMID: 26637294
2. Circadian time and lighting could be involved in the regulation of the expression of melatonin receptors MTNR3 and Rorc. PMID: 25189895
3. Mt3 may act through PDE3a to play a key role in Zinc dyshomeostasis and cell death in streptozotocin-treated islets. PMID: 25054451
4. Zn released from MT3 may contribute to VEGF induction. PMID: 23962989
5. The entire MT3 peptide shows a high capacity to bind Cu(+) , provided that this occurs in a nonoxidative milieux. This reflects a peculiar property of this MT isoform, which senses different Cu contents in the environment in which it is synthesized. PMID: 24479872
6. MT-III can help protect against light-induced retinal damage compared to MT-I/II. Some of these effects may be exerted by its antioxidative potency. PMID: 23132798
7. MT-3 is able to alter the Tg2576 phenotype in several aspects such as mortality and behavior in a gender-dependent manner. PMID: 22722772
8. ZnMt3 in cultured astrocytes may be a normal component of c-Abl activation in EGF receptor signaling PMID: 21900236
9. Metallothionein-III null mice show attenuation of cadmium-induced severe testicular toxicity, suggesting that lack of MT-III contributes to protection of testis from cadmium. PMID: 20851133
10. results indicate that MT3 may play a key role in normal lysosomal function in cultured astrocytes PMID: 20544854
11. findings indicate that abnormalities of psychological behavior were observed in the MT-3 knock-out mice PMID: 19799968
12. engineered protein has neuroinhibitory activity when introduced into metallothionein-1 PMID: 12130647
13. a correct MTs homeostasis is pivotal for brain-endocrine-immune response in order to reach successful ageing. PMID: 12714242
14. Metallothionein 3 [Mt3]-null mice had increased expression of neurotrophins as well as GAP-43 following cryoinjury. Thus MT-III does not affect the inflammatory response, but it may influence neuronal regeneration during recovery PMID: 12758064
15. MT-III isoform, which has a limited tissue distribution, especially in the central nervous system, seems to be implicated in tissue repair and/or protection against critical tissue injury PMID: 17435258
16. These findings indicate that neuronal damage was aggravated by reperfusion injury in the MT-III KO mice compared with the wild-type mice, suggesting that MT-III plays anti-oxidative and neuroprotective roles in transient cerebral ischemia. PMID: 19635467

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KEGG: mmu:17751

STRING: 10090.ENSMUSP00000034211

UniGene: Mm.2064