ncoa2 Antibody

Code CSB-PA015540XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) ncoa2 Polyclonal antibody
Uniprot No.
Target Names
ncoa2
Alternative Names
ncoa2 antibody; grip1 antibody; src2 antibody; tif2 antibody; Nuclear receptor coactivator 2 antibody; NCoA-2 antibody; NCoA2 antibody; Glucocorticoid receptor-interacting protein 1 antibody; Steroid receptor coactivator 2 antibody; Transcriptional intermediary factor 2 antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) ncoa2 protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). Has a role in primitive myelopoiesis in the differentiation of granulocytes and macrophages. May play a role in the positive regulation of the circadian clock.
Gene References into Functions
  1. The tif2 is involved in embryogenesis and in primitive hematopoiesis. tif2-knockdown zebrafish embryos are smaller than controls. PMID: 18295965
Subcellular Location
Nucleus.
Protein Families
SRC/p160 nuclear receptor coactivator family
Tissue Specificity
Expressed ubiquitously in the embryo and in many adult tissues including the brain, gills, liver, swim bladder and skin. Shows highest expression in the ovary and testis, and lower expression in the intestine, eye and skin. Only isoform E20b is expressed
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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