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Nuclear receptor coactivator 2 is a protein in humans that is encoded by NCOA2 gene. Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy balance between white and brown adipose tissues. Critical regulator of glucose metabolism regulation, acts as RORA coactivator to specifically modulate G6PC expression. Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3. Positively regulates the circadian clock by acting as a transcriptional coactivator for the CLOCK-ARNTL/BMAL1 heterodimer (By similarity).
The following NCOA2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NCOA2 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA006558 | Phospho-NCOA2 (S736) Antibody |
Human | WB, IHC, ELISA |
| CSB-PA006559 | NCOA2 Antibody |
Human | IHC, ELISA |
NCOA2 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA015540XA01DIL | ncoa2 Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
NCOA2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP015540XBF CSB-EP015540XBF CSB-BP015540XBF CSB-MP015540XBF CSB-EP015540XBF-B |
Recombinant Xenopus tropicalis Nuclear receptor coactivator 2 (ncoa2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCOA2 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP015540MO CSB-EP015540MO CSB-BP015540MO CSB-MP015540MO CSB-EP015540MO-B |
Recombinant Mouse Nuclear receptor coactivator 2 (Ncoa2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCOA2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP015540DIL CSB-EP015540DIL CSB-BP015540DIL CSB-MP015540DIL CSB-EP015540DIL-B |
Recombinant Danio rerio Nuclear receptor coactivator 2 (ncoa2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCOA2 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP015540RA CSB-EP015540RA CSB-BP015540RA CSB-MP015540RA CSB-EP015540RA-B |
Recombinant Rat Nuclear receptor coactivator 2 (Ncoa2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCOA2 Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP015540XBE CSB-EP015540XBE CSB-BP015540XBE CSB-MP015540XBE CSB-EP015540XBE-B |
Recombinant Xenopus laevis Nuclear receptor coactivator 2 (ncoa2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCOA2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP015540HU CSB-EP015540HU CSB-BP015540HU CSB-MP015540HU CSB-EP015540HU-B |
Recombinant Human Nuclear receptor coactivator 2 (NCOA2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
