Nmdar1 Antibody

Datasheet

Code	CSB-PA634509XA01DLU
Size	US$299
Image	Western Blot Positive WB detected in: recombinant protein All lanes: Nmdar1 Antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 34 kDa Observed band size: 34 kDa
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Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) Nmdar1 Polyclonal antibody

Uniprot No.

Q24418

Target Names

Nmdar1

Alternative Names

Glutamate [NMDA] receptor subunit 1 (DNMDAR-I) (dNR1) Nmdar1 nmr NR1 CG2902

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) Nmdar1 protein (291-573)

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. Plays a role in associative learning and in long-term memory consolidation.

Gene References into Functions

Recent studies indicate that several risk genes for schizophrenia are within two degrees of separation from the N-methy-D-aspartate receptor (NMDAR), a subtype of glutamate receptor that is critical to synapse formation and synaptic plasticity.[review] PMID: 26954593
NMDAR1 promotes sleep regulation in Drosophila. PMID: 26023770
NMDA Receptor 1 plays a role in both behavioral responses to touch and in the formation of the actin-rich sensory filopodia. PMID: 23103192
The study suggested that Mg(2+) block of NMDARs functions to suppress basal expression of a CREB repressor, thus permitting CREB-dependent gene expression upon LTM induction. PMID: 22681692
NMDA receptor (dNR1) mediate associative olfactory learning and memory in Drosophila PMID: 15823532
nmda receptor 1 regiure for long-term memory consolidation in Drosophila ellipsoid body. PMID: 17982450
Distribution of the NR1 subunit of the NMDA receptor in the cerebral ganglia of the honeybee and fruit fly are similar; areas with the highest concentrations of NR1 subunits were identified and compared. PMID: 18401728

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Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, postsynaptic density.

Protein Families

Glutamate-gated ion channel (TC 1.A.10.1) family

Tissue Specificity

Highly expressed in adult heads: in the brain and ring gland. Low expression throughout the entire brain is also seen. Higher expression levels were observed in some scattered cell bodies and part of their fibers, including those from several pairs of DPM

Database Links

KEGG: dme:Dmel_CG2902

STRING: 7227.FBpp0078410

UniGene: Dm.3670

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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Nmdar1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background