Nos Antibody

Code CSB-PA635657XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Nos Polyclonal antibody
Uniprot No.
Target Names
Nos
Alternative Names
Nos antibody; CG6713 antibody; Nitric oxide synthase antibody; EC 1.14.13.39 antibody; dNOS antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Nos protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. Truncated isoforms (isoform 3-isoform 6) are able to form intracellular complexes with the full-length protein and serve as dominant negative inhibitors of the enzyme activity.
Gene References into Functions
  1. Here we demonstrate that the Drosophila relaxin receptor homolog Lgr3, a leucine-rich repeat-containing G-protein-coupled receptor, is required for Dilp8-dependent growth coordination and developmental delay during the regeneration checkpoint; we demonstrate that Lgr3 activity in both the CNS and PG is necessary for NOS activation in the PG following damage PMID: 27558136
  2. Nitric Oxide Synthase Regulates Growth Coordination During Drosophila melanogaster Imaginal Disc Regeneration PMID: 26081194
  3. Hb9 governs neuronal specification and differentiation and activates expression of Nos and fd59a in the Drosophila CNS PMID: 24512689
  4. Nitric oxide synthase is not essential for Drosophila development. PMID: 20178753
  5. biochemical characterization of Drosophila nitric oxide synthase PMID: 12804606
  6. Oxygenase domain of Drosophila melanogaster Nos: unique kinetic parameters enable a more efficient NO release. PMID: 17900148
  7. Reductase domain of Drosophila melanogaster Nos: redox transformations, regulation, and similarity to mamalian homologues. PMID: 17900149
  8. The suppressed enzyme expression was shown to affect the cell polarity and movement as well as the structural pattern of organs during Drosophila development. PMID: 19326842

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Protein Families
NOS family
Database Links

KEGG: dme:Dmel_CG6713

STRING: 7227.FBpp0099922

UniGene: Dm.2707

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