NRD1 Antibody

1. Antisense transcription is specifically suppressed by Nrd1, a yeast termination factor. PMID: 26578558
2. Nrd1 and Nab3 function is tightly integrated with the nutrient response, and indicates a role for these proteins in the regulation of many mRNA coding genes. PMID: 24393166
3. Rrp6 acts with the NNS complex globally to promote transcription termination in addition to 3' end RNA processing and/or degradation at specific targets PMID: 25680078
4. Determination of the solution structure of a two-domain RNA-binding fragment of Nrd1. PMID: 24860164
5. NRd1 specific interaction with RNA polymerase II C-terminal domain is crucial in choosing RNA polymerase II termination pathway. PMID: 24196955
6. Study shows that ncRNA transcription in the yeast S. cerevisiae is globally restricted by early termination that relies on the essential RNA-binding factor Nrd1. PMID: 24210918
7. a multiplicity of interactions is needed to assemble a higher order Nrd1-Nab3 complex that coats specific nascent RNAs in preparation for termination. PMID: 24100036
8. a role for Nrd1 in regulating the cellular response to nutrient availability PMID: 22431520
9. structure reveals a direct recognition of pSer5 by Nrd1 that requires the cis conformation of the upstream pSer5-Pro6 peptidyl-prolyl bond of the CTD PMID: 22892239
10. The results demonstrate that the function of the Tlc1 terminator region depends on the Nrd1/Nab3 transcription termination pathway. PMID: 22379137
11. We report the resonance assignment of CTD-interacting domain (CID) of pre-mRNA down-regulation (Nrd)1 bound to Ser5-phosphorylated CTD (pSer5) of RNA Polymerase II. PMID: 21350922
12. both RNA-binding motifs of Nab3 and Nrd1 alone bind their termination elements with a weak affinity. Interestingly, when Nab3 and Nrd1 form a heterodimer, the affinity to RNA is significantly increased due to the cooperative binding. PMID: 21084293
13. Nrd1 may link transcription and RNA 3' end formation with surveillance by the exosome. PMID: 16427013
14. NRD1 expression is regulated by Nrd1- and Nab3-directed premature termination. PMID: 16507362
15. Nrd1 and Nab3 are required for transcription termination of cryptic unstable transcripts (CUTs). PMID: 16973436
16. The Nrd1p-Nab3p-dependent pathway, involved in transcription termination of sno/snRNAs, is required for efficient degradation of NEL025c RNAs and other cryptic unstable transcripts. PMID: 16973437

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KEGG: sce:YNL251C

STRING: 4932.YNL251C