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Ogg1 Antibody

Datasheet
Code CSB-PA893702XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Ogg1 Polyclonal antibody
Uniprot No.
Q9V3I8
Target Names
Ogg1
Alternative Names
Ogg1 antibody; CG1795 antibody; N-glycosylase/DNA lyase antibody; dOgg1) [Includes: 8-oxoguanine DNA glycosylase antibody; EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase antibody; AP lyase antibody; EC 4.2.99.18)] antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Ogg1 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Related Products

Ogg1 Proteins

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Target Background

Function
DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. Efficiently incises DNA duplexes containing 8-hydroxyguanine (8-OH-Gua), 8-hydroxyadenine (8-OH-Ade) and abasic (AP) sites placed opposite to a cytosine.
Gene References into Functions
  1. dOgg1 and RpS3 in mitochondria increase cell survival after exposure to the nitric oxide donor SNAP PMID: 16895796
Subcellular Location
Nucleus. Cytoplasm. Note=Nuclear and cytoplasmic in nurse cells and oocyte.
Protein Families
Type-1 OGG1 family
Tissue Specificity
Expressed in the cytoplasm of the nurse cells from oogenesis stage 3 and in the oocyte cytoplasm from stage 10B onwards. Expressed uniformly in third larval instar wing imaginal disk.
Database Links

KEGG: dme:Dmel_CG1795

STRING: 7227.FBpp0071168

UniGene: Dm.3084

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Related Articles
Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?
Related pathways
DNA repair pathway
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