RIM21 Antibody

Code CSB-PA344146XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RIM21 Polyclonal antibody
Uniprot No.
Target Names
RIM21
Alternative Names
RIM21; PAL2; YNL294C; N0466; pH-response regulator protein palH/RIM21; Regulator of IME2 protein 21
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RIM21 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH. Required for growth at alkaline pH.
Gene References into Functions
  1. The C-terminal cytosolic domain of Rim21 was associated with the plasma membrane under normal conditions but dissociated upon alterations in lipid asymmetry. PMID: 26527678
  2. plasma membrane depolarization seems to be one of the key signals for the pH sensor molecule Rim21 PMID: 23019326
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
PalH/RIM21 family
Database Links

KEGG: sce:YNL294C

STRING: 4932.YNL294C

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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