pelo Antibody

Code CSB-PA773834XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) pelo Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
peloProtein pelota homolog antibody; EC 3.1.-.- antibody
Raised in
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) pelo protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Purification Method
Protein A/G
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Cotranslational quality control factor involved in the No-Go Decay (NGD) pathway. Required for 48S complex formation from 80S ribosomes and dissociation of vacant 80S ribosomes. Recognizes stalled ribosomes and promotes dissociation of elongation complexes assembled on non-stop mRNAs; this triggers endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and to degrade damaged mRNAs as part of the No-Go Decay (NGD) pathway. Upon mitochondrial damage is recruited to the ribosome/mRNA-ribonucleoprotein complex associated to mitochondrial outer membrane thereby enabling the recruitment of autophagy receptors and induction of mitophagy.
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Eukaryotic release factor 1 family, Pelota subfamily
Database Links
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
7505 Fannin St., Ste 610, Room 322 (CUBIO Innovation Center), Houston, TX 77054, USA
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