PEX5 Antibody

Code CSB-PA872288XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) PEX5 Polyclonal antibody
Uniprot No.
Target Names
PEX5
Alternative Names
PEX5 antibody; At5g56290 antibody; MXK23.3 antibody; Peroxisome biogenesis protein 5 antibody; Peroxin-5 antibody; AtPEX5 antibody; Peroxisomal targeting signal type 1 receptor antibody; Pex5p antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana PEX5 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Import receptor for peroxisomal-targeting signal one (PTS1). A receptor-cargo complex composed of PEX5, PEX7, a PTS1-containing protein and a PTS2-containing protein is targeted to peroxisomes during import. Necessary for the developmental elimination of obsolete peroxisome matrix proteins.
Gene References into Functions
  1. PEX5 binding to the PEX14N-terminal domain (PEX14N) has no effect on the affinity of PEX5 for a PTS1 containing peptides. PMID: 24879895
  2. PEX7 facilitates PEX5 accumulation and import of PTS1 cargo into peroxisomes PMID: 20130089
  3. Pex5p and Pex7p play different roles in the maintenance of glyoxysomal and leaf peroxisomal functions in plants PMID: 15637057
  4. Pex5p recognizes Cat1 in a manner distinct from typical PTS1. PMID: 18308759
  5. The Arabidopsis pex5-1 mutant is specifically defective in PTS2 (but not PTS1) protein import into peroxisomes, probably because of reduced interaction with the PEX7 PTS2 receptor. PMID: 15548601
  6. A genetic screen for peroxisome defective mutants revealed a pex5 mutant that is sucrose dependent during germination and resistant to the inhibitory effects of IBA on root elongation. PMID: 11063705

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Subcellular Location
Cytoplasm. Peroxisome membrane; Peripheral membrane protein.
Protein Families
Peroxisomal targeting signal receptor family
Tissue Specificity
Expressed in flowers, siliques, leaves and roots.
Database Links

KEGG: ath:AT5G56290

STRING: 3702.AT5G56290.1

UniGene: At.10824

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