PEX7 Antibody

Code CSB-PA017808XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PEX7 Polyclonal antibody
Uniprot No.
Target Names
PEX7
Alternative Names
PEX7 antibody; PAS7 antibody; PEB1 antibody; YDR142C antibody; YD2943.01C antibody; YD9302.18C antibody; Peroxisomal targeting signal 2 receptor antibody; PTS2 receptor antibody; Peroxin-7 antibody; Peroxisome import protein PAS7 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PEX7 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import essential for import of 3-oxoacyl-CoA thiolase (a PTS2-containing protein) into peroxisomes. May direct thiolase to peroxisomes by shuttling between the cytosol and peroxisomal membranes.
Gene References into Functions
  1. appending GFP to Pex7p's COOH terminus shifts Pex7p's intracellular distribution from predominantly cytosolic to predominantly peroxisomal in Saccharomyces cerevisiae PMID: 15545321
  2. the C terminus of Pex14p contains distinct Pex5p and one Pex7p binding sites and the N terminus could be involved in a Pex5p-Pex14p association inside the peroxisomal membrane PMID: 16107331
  3. Data strongly suggest that the formation of the ternary cytosolic PTS2 pre-import complex occurs hierarchically. PMID: 19183303
Subcellular Location
Cytoplasm. Peroxisome.
Protein Families
WD repeat peroxin-7 family
Database Links

KEGG: sce:YDR142C

STRING: 4932.YDR142C

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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