PP2A5 Antibody

Code CSB-PA520810XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) PP2A5 Polyclonal antibody
Uniprot No.
Target Names
PP2A5
Alternative Names
PP2A5 antibody; At1g69960 antibody; F20P5.30 antibody; T17F3.1 antibody; Serine/threonine-protein phosphatase PP2A-5 catalytic subunit antibody; EC 3.1.3.16 antibody; Protein phosphatase 2A isoform 5 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana PP2A5 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Associates with the serine/threonine-protein phosphatase PP2A regulatory subunits A and B' to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosphorylating peroxisomal beta-oxidation-related proteins. Involved in the positive regulation of salt stress responses. May function by increasing chloride channel activities on vacuolar membranes.
Gene References into Functions
  1. data indicate that PP2A-C5-mediated better growth under salt conditions might involve up-regulation of CLC activities on vacuolar membranes and that PP2A-C5 could be used for improving salt tolerance in crops. [PP2A-C5] PMID: 27676158
  2. The PP2A inhibitor phosphorylated alpha-endosulfine (ENSA)/ARPP-19 is highly conserved across plant species. ENSA/ARPP-19 is only expressed in a selection of Arabidopsis thaliana tissues. PMID: 25666948
  3. Phosphatidic acid interacts with the scaffolding A1 subunit of Protein Phosphatase 2A (PP2A) and regulates PP2A-mediated PIN1 dephosphorylation in Arabidopsis. PMID: 23686948
  4. PP2A exerts multilevel control on HMGR through the five-member B'' protein family during normal development and in response to a variety of stress conditions. PMID: 21478440
  5. PP2A directly interacts with the ACS6 protein, and PP2A complexes dephosphorylate a carboxy-terminal ACS6 phosphopeptide in vitro. PMID: 21533019
  6. Data reveal a crucial function for PP2A in dephosphorylating and activating BZR1 and completes the set of core components of the brassinosteroid-signalling cascade from cell surface receptor kinase to gene regulation in the nucleus. PMID: 21258370

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Subcellular Location
Cytoplasm, cytosol. Peroxisome.
Protein Families
PPP phosphatase family, PP-2A subfamily
Database Links

KEGG: ath:AT1G69960

STRING: 3702.AT1G69960.1

UniGene: At.20106

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