Rala Antibody

1. data indicate that Ral and the exocyst regulate autophagy in a context-dependent manner, and that in dying salivary glands, Ral mediates autophagy, at least in part, by regulation of Notch. PMID: 26598552
2. These studies identify a pathway, which stretches from Rab8 to RalA and the exocyst complex, that mediates rapid furrow formation in early Drosophila embryos. PMID: 26092850
3. Constitutively active Ral expressed in muscle causes the exocyst to be concentrated in the region surrounding synaptic boutons and consequently enlarges the membrane folds of the postsynaptic plasma membrane. PMID: 23812009
4. the Rap1-Rgl-Ral signaling network is a novel mechanism that cooperates with other intrinsic polarity cues to modulate asymmetric neuroblast division PMID: 22084305
5. prevention of ligand-independent Notch activation is not simply a constitutive process, but is a target for regulation by Ral during cell fate specification and pattern formation. PMID: 21350007
6. Abnormalities of the Wnt5/5a pathway (located in the apical ectodermal ridge as well as in the mesoderm) will affect chondrogenesis of the developing limb and experimental Wnt5a(-/-) limbs have terminal adactyly. PMID: 20709709
7. the Ral-centered protein network appears to be extremely conserved in human and flies PMID: 12529414
8. The identification and characterization of a DBL-like guanine nucleotide exchange factor (GEF) in Drosophila, called GEFmeso, as a novel binding target of the Ras-like GTPase Ral. PMID: 16581976
9. RalA is required in organizing centres to control proper patterning and migration in vivo. PMID: 18552769

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KEGG: dme:Dmel_CG2849

STRING: 7227.FBpp0070558

UniGene: Dm.1689