Rho1 Antibody

1. Study identified circadian rhythms in Rho1 GTPase activity in s-LNv axons that are regulated by rhythmic transcription of Pura, a Rho1 GEF. Pura activates Rho1 to retract s-LNv axons, decrease active zone numbers and reduce s-LNvs' influence on the clock network. Thus, study links transcription, plasticity, network hierarchy and behavior. PMID: 26234154
2. As tension in the epithelial layer increases, Rho kinase signaling activates myosin assembly and contraction in the developing Drosophila egg chamber. PMID: 24943847
3. This work identifies spatially distinct functions for Rho1 in the regulation of DE-cadherin-containing vesicular trafficking during adherens junctions remodeling in live epithelia. PMID: 25079692
4. impaired Hippo signaling induces JNK activation through Rho1. PMID: 25583514
5. Galpha73B is a downstream effector of JAK/STAT signaling and a regulator of Rho1 in Drosophila hematopoiesis. PMID: 24163435
6. The RhoA fails to form a compact ring in late cytokinesis after Sti depletion, and this function requires Sti kinase activity. PMID: 22084308
7. removal of a single copy of rho1 can suppress the pak phenotype PMID: 21098722
8. Results suggest that Crossveinless-c contributes to sprouting and subsequent growth of the anterior-posterior-oriented branches through negative regulation of Rho1. PMID: 20384791
9. Continuous autophagy was required for integrin-mediated hemocyte spreading and Rho1-induced cell protrusions. PMID: 20498061
10. disruption of Rho1 suppresses apical constriction and invagination in Adenomatous polyposis coli null cells PMID: 20102708
11. Results suggest that Rho1 functions at the cell cortex to regulate JNK activity and implicate Rho1 and moesin in epithelial cell survival. PMID: 20404112
12. analysis of second-site noncomplementation screen for modifiers of Rho1 signaling during imaginal disc morphogenesis in Drosophila PMID: 19862331
13. Drosophila RhoA regulates the cytoskeleton and cell-cell adhesion in the developing epidermis. PMID: 12070092
14. While Rho1 protein is present throughout the cell, it accumulates apically, particularly at sites of cadherin-based adherens junctions. PMID: 12135916
15. RhoA and Sb-sbd act in a common pathway during leg morphogenesis PMID: 14668391
16. role for Rho1 in regulating signaling events governing proper patterning during development PMID: 15649467
17. Taken together, these findings suggest that RhoGEF4 may participate in cytoskeleton-related cellular events by specifically activating RhoA in neuronal morphogenesis. PMID: 17011730
18. Reducing activity of Rho1 from somatic support cells suppressed the germ cell enclosure defects of the conditional Spitz allele. PMID: 17629483
19. In parallel to regulation of crb RNA and protein, Rho1 activity also signals through Rho-kinase (Rok) to induce apical constriction and cell shape change during invagination of salivary gland. PMID: 18585373
20. Results demonstrate that Rho1 is required to maintain adherens junction integrity independent of its role in sustaining apical cell tension. PMID: 19506041
21. in addition to its interaction with Mwh Rho1 has functions in wing planar polarity that are parallel to and upstream of fz. PMID: 19576201

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KEGG: dme:Dmel_CG8416

STRING: 7227.FBpp0086354

UniGene: Dm.644