rppH Antibody

1. it was also determined that diphosphorylated mRNA decay intermediates are abundant in wild-type E. coli and that their fractional level increases to almost 100% for representative mRNAs in mutant cells lacking RppH. PMID: 29619898
2. study examined phenotypes of the rppH mutant strain to define the physiological role of RppH in more detail; through various phenotypic analyses of the rppH mutant, found the rppH mutant cells have increased envelope permeability; propose that RppH is associated with regulation of envelope integrity PMID: 28859318
3. Triphosphate-to-monophosphate conversion to induce 5' end-dependent RNA degradation is a two-step process in E. coli involving gamma-phosphate removal by an unidentified enzyme to enable subsequent beta-phosphate removal by RppH. PMID: 28673541
4. Data show that the specificity of RNA pyrophosphohydrolase RppH is species-dependent. PMID: 25657006
5. Data indicate that X-ray structures of RNA pyrophosphohydrolase RppH have revealed molecular features important for RNA recognition. PMID: 25657011
6. The data suggest that the cellular level of DapF is a critical factor regulating the RppH-catalyzed pyrophosphate removal and the subsequent degradation of target mRNAs. PMID: 25313159
7. RppH not only catalyses a process functionally reminiscent of eukaryotic mRNA decapping but also bears an evolutionary relationship to the eukaryotic decapping enzyme Dcp2 PMID: 18202662

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KEGG: ecj:JW2798

STRING: 316385.ECDH10B_3000