RECQL4A Antibody

Datasheet

Code	CSB-PA810545XA01DOA
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Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) RECQL4A Polyclonal antibody

Uniprot No.

Q8L840

Target Names

RECQL4A

Alternative Names

RECQL4A antibody; RECQ4A antibody; RQL4A antibody; SGS1 antibody; At1g10930 antibody; T19D16.15 antibody; ATP-dependent DNA helicase Q-like 4A antibody; EC 3.6.4.12 antibody; RecQ-like protein 4A antibody; AtRecQ4A antibody; AtRecQl4A antibody; SGS1-like protein antibody; AtSGS1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana RECQL4A protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

3'-5' DNA helicase involved in DNA repair. Required for the maintenance of genome stability by modulation of the DNA damage response and repression of crossovers. Confers resistance to genotoxic stress. Suppresses spontaneous homologous recombination (HR) events in somatic cells together with its partners RMI1 and TOP3A. Contributes to the maintenance of chromosome integrity during meiosis. Involved in the removal of telomeric bridges that appear to arise during meiotic recombination. Required to resolve or dissolve MSH4-dependent telomeric associations. Does not seem required for chiasma formation.

Gene References into Functions

The N-terminus of RECQ4A was determined to be required for its specific functions in DNA repair and recombination. PMID: 24174542
Pollen viability decreased in Atrecq4A, resulting in a reduction in fertility.Immunolocalization confirmed the association of AtRECQ4A with the telomeres during prophase I. PMID: 21265901
RECQ4A and MUS81 define RAD5A-independent pathways of DNA repair. RAD5A and RECQ4A act through two independent pathways for intrastrand cross-link DNA repair. RECQ4A and MUS81 act in parallel pathways to resolve replication-associated DNA intermediates. PMID: 20971895
Roles for Arabidopsis RecQl4A in maintenance of genome stability by modulation of the DNA damage response and suppression of HR are reported. PMID: 16146519

Subcellular Location

Nucleus. Chromosome.

Protein Families

Helicase family, RecQ subfamily

Tissue Specificity

Expressed in roots, seedlings, young leaves, shoots, shoot apical mersitem, inflorescences, flowers, siliques and seeds.

Database Links

KEGG: ath:AT1G10930

STRING: 3702.AT1G10930.1

UniGene: At.10177

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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RECQL4A Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background