frr Antibody

1. Ribosome recycling after peptide chain termination is a special case of the general RRF and EF-G function, which happens whenever fMet-tRNA is not available for triggering 70S scanning. PMID: 27261258
2. Data show that monosomes produced in ribosome recycling factor-deficient cells are able to translate synthetic homopolymer but not natural mRNA with leader and canonical initiation signal. PMID: 15522083
3. data enable a model to be proposed for the dual action of EF-G and RRF during ribosome recycling PMID: 15616575
4. domain II of RRF plays a crucial role in the concerted action of RRF and EF-G for the post-termination complex disassembly, and the specific interaction between RRF and EF-G on ribosomes mainly depends on the interaction between domain II of RRF and EF-G PMID: 16262604
5. V117D mutation does not perturb the efficient interdomain interaction, which results in cooperative unfolding of the RRF protein. PMID: 16684502
6. RRF is capable of spontaneously moving from its initial binding site on the 70S ribosome to a site exclusively on the large 50S ribosomal subunit. PMID: 17643374
7. The disruption of bridge B2a upon RRF binding to the ribosome seen in the present structures reveals one of the key roles that RRF plays in ribosome recycling, the dissociation of 70S ribosomes into subunits. PMID: 18234219

Show More

Hide All

KEGG: ecj:JW0167

STRING: 316385.ECDH10B_0152