SAHH1 Antibody

Code CSB-PA522805XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SAHH1 Polyclonal antibody
Uniprot No.
Target Names
SAHH1
Alternative Names
SAHH1 antibody; EMB1395 antibody; HOG1 antibody; At4g13940 antibody; dl3010w antibody; Adenosylhomocysteinase 1 antibody; AdoHcyase 1 antibody; EC 3.3.1.1 antibody; Protein EMBRYO DEFECTIVE 1395 antibody; Protein HOMOLOGY-DEPENDENT GENE SILENCING 1 antibody; S-adenosyl-L-homocysteine hydrolase 1 antibody; SAH hydrolase 1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana SAHH1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. Required for DNA methylation-dependent gene silencing.
Gene References into Functions
  1. SAHH1 plays a critical role in methyl homeostasis, and its deficiency is a major contributing factor to the change of global gene expression, metabolic pathways and activation of transposable elements in the sahh1 mutant. PMID: 22555436
  2. A histone methylation-dependent DNA methylation pathway is uniquely impaired by deficiency in adenosylhomocysteinase. PMID: 16951055
  3. HOG1 has high affinity cytokinin binding activity. Overexpression led to early flowering with a significantly reduced plant biomass and number of leaves. PMID: 18592247
Protein Families
Adenosylhomocysteinase family
Database Links

KEGG: ath:AT4G13940

STRING: 3702.AT4G13940.1

UniGene: At.24056

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