e(y)3 Antibody

Code CSB-PA892909XA01DLU
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) e(y)3 Polyclonal antibody
Uniprot No.
Target Names
e(y)3
Alternative Names
e(y)3 antibody; l(1)G0084 antibody; SAYP antibody; CG12238 antibody; Supporter of activation of yellow protein antibody; Protein enhancer of yellow 3 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) e(y)3 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Essential transcription regulator during early development. Coactivates transcription of some euchromatin genes and repress transcription in of euchromatin genes translocated to heterochromatin.
Gene References into Functions
  1. In the repressed state of the ftz-f1 gene, the Pol II complex is pre-recruited on the promoter; Pol II starts transcription but is paused 1.5 kb downstream of the promoter, with SAYP and Brahma forming a nucleosomal barrier ahead of paused Pol II. PMID: 22638575
  2. SAYP interacts with DHR3 nuclear receptor and activates the corresponding genes by recruiting the BTFly (Brahma and TFIID) coactivator supercomplex during development and have multiple common targets across the genome. PMID: 22567850
  3. The transcription coactivators SAYP and ENY2 act in gene expression as cooperative nanoregulators,determining the molecular mechanisms of spatial and temporal coordination of the processes involved in the realization of genetic information. PMID: 22117439
  4. DHR3 and SAYP interact during development and have multiple common targets across the genome PMID: 21519192
  5. Novel conservative domain of SAYP coactivator mediates TFIID and Brahma transcriptional complexes interaction PMID: 21090241
  6. SAYP serves as a basis for assembling the BTFly nuclear supercomplex consising of the Brahma and TFIID coactivators. BTFly may play an important role in ontogenesis. PMID: 20873199
  7. SAYP is a signature subunit that plays a major role in the functional specificity of the PBAP holoenzyme. PMID: 18299390
  8. The existence of a stable coactivator supercomplex consisting of the chromatin-remodeling factor Brahma (SWI/SNF) and the transcription initiation factor TFIID, is shown. PMID: 19541607

Show More

Hide All

Subcellular Location
Nucleus. Cytoplasm. Chromosome. Note=On polytene chromosomes, it mainly localizes to transcriptionally active euchromatin sites but also localizes to heterochromatic regions such as the chromocenter and the chromosome 4. Cytoplasmic in nursing cells and growing oocytes.
Protein Families
SAYP family
Tissue Specificity
Widely expressed. Highly expressed in ovary. Expressed in nursing cells and growing oocytes at all stages of development and accumulates in mature oocytes. Expressed in the nuclei of syncytium blastoderm of early embryos and in the nuclei of different tis
Database Links
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1