SCO2 Antibody

Code CSB-PA850040XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SCO2 Polyclonal antibody
Uniprot No.
Target Names
SCO2
Alternative Names
SCO2 antibody; CYO1 antibody; At3g19220 antibody; MVI11.22Protein disulfide-isomerase SCO2 antibody; EC 5.3.4.1 antibody; Protein SNOWY COTYLEDON 2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana SCO2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Protein disulfide-isomerase involved in chloroplast development in cotyledons. Involved in the process of vesicle-derived thylakoid formation, probably at the level of the integration and folding of LHCB proteins at the initial location of integration. Acts only in germinating seeds after dormancy, during the transition from heterotrophic to autotrophic growth.
Gene References into Functions
  1. results indicate that SCO2 plays a distinct role in PSII assembly or repair and constitutes a novel factor involved in leaf variegation PMID: 28286296
  2. SCO2 interacts with LHCB1 proteins and is co-expressed with genes encoding proteins of the tetrapyrrole biosynthesis pathway. Mutations in sco2 affect the accumulation of the chlorophyll precursor protochlorophyllide. PMID: 22040291
  3. Data indicate that CYO1(At3g19220) has protein disulfide isomerase activity, and suggest that CYO1 has a chaperone-like activity required for thylakoid biogenesis in cotyledons PMID: 17921316
Subcellular Location
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein. Note=Associates with multiple thylakoid complexes.
Tissue Specificity
Expressed in roots, rosette and cauline leaves, stems, inflorescences and young siliques of light-grown plants, but not in etiolated seedlings or in senescing tissues.
Database Links

KEGG: ath:AT3G19220

STRING: 3702.AT3G19220.1

UniGene: At.26601

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