Sema2a Antibody

Code CSB-PA638761XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Sema2a Polyclonal antibody
Uniprot No.
Target Names
Sema2a
Alternative Names
Sema2a antibody; Sema-2a antibody; CG4700 antibody; Semaphorin-2A antibody; Semaphorin-II antibody; Sema II antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Sema2a protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a role in growth cones guidance. Required for both proper adult behavior and survival. Can function in vivo as a selective target-derived signal that inhibits the formation of specific synaptic terminal arbors.
Gene References into Functions
  1. PlexB is a receptor for the secreted semaphorin Sema-2a PMID: 16672342
  2. These data support a model in which Sema2a, while being secreted from oenocytes, represses axon extension from the sensory neuron cell body, but only in regions in direct contact with oenocytes. PMID: 17109838
Subcellular Location
Secreted.
Protein Families
Semaphorin family
Tissue Specificity
Transiently expressed by a single large muscle during motoneuron outgrowth and synapse formation.
Database Links

KEGG: dme:Dmel_CG4700

STRING: 7227.FBpp0086237

UniGene: Dm.14046

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