Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SKOR Polyclonal antibody

Uniprot No.

Q9M8S6

Target Names

SKOR

Alternative Names

SKOR antibody; At3g02850 antibody; F13E7.21 antibody; Potassium channel SKOR antibody; Stelar K(+) outward rectifying channel antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana SKOR protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Target Background

Function

Highly selective outward-rectifying potassium channel. Involved in potassium release into the xylem sap toward the shoots. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by depolarization. The voltage-dependence of the channel is abolished by internal or external acidification. May interact with the cytoskeleton or with regulatory proteins.

Gene References into Functions

Data show that nutritional conditions as a critical factor for the joint activity of Arabidopsis proteins SKOR and NPF7.3/NRT1.5 for shoot potassium (K) homeostasis. PMID: 26508776
Study found that, in particular, the N-terminal part of the S5 played a critical role in KAT1 and SKOR gating. PMID: 20007672
A minimal cysteine motif required to activate the SKOR K+ channel of Arabidopsis by the reactive oxygen species H2O2. PMID: 20605786
Phosphatidylinositol phosphates were identified as essential regulators for the voltage-dependent and -independent activation of A. thaliana potassium channels expressed in X. laevis oocytes. PMID: 15842627
The intracellular potassium sensing mechanism couples SKOR activity to potassium nutrition status in the 'source cells', establishing a supply-based unloading system for the regulation of potassium distribution. PMID: 16623888
Mapping the SKOR sequence to the crystal structure of the voltage-dependent K+ channel suggests interaction between the S6 gating domain and the base of the pore helix, a prediction supported by mutations at this site. PMID: 16623889
Single mutations in SKOR convert it from an outward K+ channel into an inward K+ channel. PMID: 18287042

Hide All

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

Potassium channel family, Plant (TC 1.A.1.4) subfamily

Tissue Specificity

Expressed in root pericycle and xylem parenchyma, and in flower at a lower level.

Database Links

KEGG: ath:AT3G02850

STRING: 3702.AT3G02850.1

UniGene: At.41071

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：

Code	CSB-PA864960XA01DOA
Size	Enquire
Have Questions?	Leave a Message or Start an on-line Chat

SKOR Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background