Stat92E Antibody

1. critical in vivo regulator of glial responsiveness to axonal injury PMID: 25369313
2. educed Wingless (Wg) signaling dominantly inhibits Stat92E activity in the hinge PMID: 23978534
3. stat92E activity is regulated along the proximodistal axis to pattern this axis and control the relative expansion of the pouch, hinge, and notum in developing Drosophila PMID: 23499656
4. modulating STAT activity levels regulates competitor status PMID: 22992954
5. Loss of Stat92E in the early embryo down-regulates early zygotic genes important for pattern formation. PMID: 21637778
6. sumoylation has a repressive role in the regulation of the JAK/STAT pathway PMID: 20616536
7. Characterization of Stat92E that promotes tunmorigenesis in Drosophila is reported. PMID: 20501334
8. An efficient approach to isolate STAT regulated enhancers uncovers STAT92E fundamental role in Drosophila tracheal development. PMID: 20171201
9. signal activates the JAK/STAT92E pathway in neighboring epithelial cells, causing them to become invasive. PMID: 11779460
10. stat92E is necessary for the early differentiation of follicle cells during Drosophila oogenesis PMID: 11846485
11. Negative regulation of STAT92E by an N-terminally truncated STAT protein derived from an alternative promoter site. PMID: 12231627
12. Taken together with the appearance of STAT92E in a gradient in the hindgut epithelium, these results support a model in which an anteroposterior gradient of ligand results in a gradient of activated STAT. PMID: 12441298
13. stat92E mutants are defective in tracheal formation, hindgut elongation, and nervous system development PMID: 14654218
14. A genetic analysis was made of Stat92E to larval hemocyte concentration and the egg encapsulation response. PMID: 15082553
15. direct evidence that the JAK/STAT pathway mediates a key signal from the somatic gonad that regulates male germline sexual development PMID: 16049490
16. STAT signalling controls cell motility during germ cell migration. PMID: 16477645
17. Study shows that although STAT directly regulates Sxl establishment promoter (SxlPe), it is dispensable for promoter activation, instead, JAK/STAT is needed to maintain high-level SxlPe expression in order to ensure Sxl autoregulation in XX embryos. PMID: 17363251
18. Study examines the natural DNA-binding sites of the single Drosophila Stat and show that Stat92E is able to bind to and activate target gene expression through palindromic sites separated by spacers of both three or four nucleotides. PMID: 18802449
19. Genome-wide expression profiling on eye discs in which Stat92E is hyperactivated, revealed 584 differentially regulated genes. PMID: 19504457
20. STAT92E activity is restricted to hub-proximal germ cells. STAT92E activation appears to be necessary to promote male germline stem cell establishment & for onset of self-renewing GSC divisions. PMID: 19643104
21. JAK/STAT signaling regulates tissue outgrowth and male germline stem cell fate in Drosophila. PMID: 15686618

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KEGG: dme:Dmel_CG4257

STRING: 7227.FBpp0088489

UniGene: Dm.2627