STM1 Antibody

Datasheet

Code	CSB-PA334507XA01SVG
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Product Details

Full Product Name

Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) STM1 Polyclonal antibody

Uniprot No.

P39015

Target Names

STM1

Alternative Names

STM1 antibody; MPT4 antibody; STO1 antibody; YLR150W antibody; L9634.1 antibody; Suppressor protein STM1 antibody; 3BP1 antibody; GU4 nucleic-binding protein 2 antibody; G4p2 protein antibody; POP2 multicopy suppressor protein 4 antibody; Ribosomal subunits association factor antibody; AF antibody; TOM1 suppressor protein 1 antibody; Triplex-binding protein 1 antibody

Raised in

Rabbit

Species Reactivity

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Immunogen

Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) STM1 protein

Immunogen Species

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Binds specifically G4 quadruplex (these are four-stranded right-handed helices, stabilized by guanine base quartets) and purine motif triplex (characterized by a third, antiparallel purine-rich DNA strand located within the major groove of a homopurine stretch of duplex DNA) nucleic acid structures. These structures may be present at telomeres or in rRNAs. Acts with CDC13 to control telomere length homeostasis. Involved in the control of the apoptosis-like cell death.

Gene References into Functions

These findings suggest that Stm1p can act as a ribosome preservation factor under conditions of nutrient deprivation and restoration. PMID: 23206692
Stm1 may recognize the shape of the triplex rather than the base sequence of the triplex. PMID: 18776278
Stm(amino acids 1-113) is the minimal domain to specifically bind with the purine motif triplex. PMID: 18029617
Stm1 loss-of-function alleles and overexpression strains show several genetic interactions with Pat1 and Dhh1 alleles in a manner consistent with Stm1 working upstream of Dhh1 to promote Dhh1 function. PMID: 19015546
data indicates that Stm1p plays a complementary role to eEF3 in translation. PMID: 19666721

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Subcellular Location

Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Note=Concentrated in the perinuclear region.

Database Links

KEGG: sce:YLR150W

STRING: 4932.YLR150W

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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STM1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background