SYP121 Antibody

Code CSB-PA135304XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SYP121 Polyclonal antibody
Uniprot No.
Target Names
SYP121
Alternative Names
SYP121 antibody; SYR1 antibody; At3g11820 antibody; F26K24.11 antibody; Syntaxin-121 antibody; AtSYP121 antibody; Syntaxin-related protein At-Syr1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana SYP121 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Vesicle trafficking protein that functions in the secretory pathway.
Gene References into Functions
  1. Clathrin and SYP121 functions are important for the coordination of endocytosis and exocytosis and have an impact on stomatal function, gas exchange, and vegetative growth in Arabidopsis (Arabidopsis thaliana). PMID: 28830938
  2. The domain of SEC11 that bound the SYP121 N terminus was itself able to block secretory traffic in the wild type and syp122 but not in syp121 mutant Arabidopsis. PMID: 25747882
  3. Post-Golgi trafficking of PIP2;7 involves interactions with Qc-SNARE SYP61 and Qa-SNARE SYP121. The proper delivery of PIP2;7 to the plasma membrane depends on the activity of the two SNAREs, and that the SNAREs colocalize and physically interact. PMID: 25082856
  4. ATL31 plays an important role in connecting the Carbon/Nitrogen response with basal immunity by promoting papilla formation through its association with SYP121. PMID: 24394775
  5. SYP121 facilitates stomatal reopening and they suggest that K channel traffic and recycling to the plasma membrane underpins the stress memory phenomenon of programmed closure in stomata. PMID: 21914010
  6. Data indicate that SEC11 (At1g12360) binds directly with SYP121 (At3g11820) both in vitro and in vivo to affect secretory traffic. PMID: 23572542
  7. SNARE interaction with the KC1 K+ channel depends on the presence of the N terminus of SYP121. PMID: 20884800
  8. SYP121 is needed to promote channel gating, AKT1-associated K+ current, K+ uptake at the root epidermis, and for growth when channel-mediated K+ uptake is limiting. It also interacts selectively with KC1. PMID: 19794113
  9. SYP122 may have a general function in secretion and a role in cell wall deposition, while its homolog PEN1 appears to have a basal function in secretion and a specialized defense-related function [PEN1] PMID: 15342780
  10. Activity determinants and functional specialization of Arabidopsis PEN1 syntaxin in innate immunity. PMID: 18678865

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Subcellular Location
Cell membrane; Single-pass type IV membrane protein.
Protein Families
Syntaxin family
Database Links

KEGG: ath:AT3G11820

STRING: 3702.AT3G11820.1

UniGene: At.11000

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