Snake venom metalloproteinase leucurolysin-A Antibody

Code CSB-PA308157ZA01BIY
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Product Details

Full Product Name
Rabbit anti-Bothrops leucurus (Whitetail lancehead) Snake venom metalloproteinase leucurolysin-A Polyclonal antibody
Uniprot No.
Target Names
Snake venom metalloproteinase leucurolysin-A
Alternative Names
Snake venom metalloproteinase leucurolysin-A (Leuc-A) (SVMP) (EC 3.4.24.-)
Raised in
Rabbit
Species Reactivity
Bothrops leucurus
Immunogen
Recombinant Bothrops leucurus Snake venom metalloproteinase leucurolysin-A protein
Immunogen Species
Bothrops leucurus (Whitetail lancehead)
Conjugate
Non-conjugate
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Non-hemorrhagic metalloproteinase that hydrolyzes the alpha chains of fibrinogen, as well as fibrin, fibronectin and casein. Beta and gamma chains are also hydrolyzed, but more slowly. Thrombolytic activity is also observed. Induces detachment of endothelial cells followed by death, and inhibits endothelial cell adhesion to fibronectin. Induces edema in mouse paw. Inhibits ADP-induced platelet aggregation on human platelet-rich plasma with an IC(50) of 2.8 uM.
Subcellular Location
Secreted.
Protein Families
Venom metalloproteinase (M12B) family, P-I subfamily
Tissue Specificity
Expressed by the venom gland.
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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