Taf1 Antibody

Code CSB-PA023076XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Taf1 Polyclonal antibody
Uniprot No.
Target Names
Taf1
Alternative Names
Taf1 antibody; TAF250 antibody; CG17603 antibody; Transcription initiation factor TFIID subunit 1 antibody; EC 2.7.11.1 antibody; TAFII250 antibody; TBP-associated factor 230 kDa antibody; p230 antibody; Transcription initiation factor TFIID 230 kDa subunit antibody; TAFII-230 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Taf1 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp.
Gene References into Functions
  1. TAF1 is involved in both establishing an upper limit of transcription during induction and efficiently turning the gene off once the inducer is removed PMID: 23610421
  2. results suggest stepwise assembly of a testis-specific TFIID complex (tTFIID) whereby a TAF1 isoform, presumably TAF1-2, is recruited to a core subassembly of tTAFs in spermatocyte nucleoli PMID: 17823958
  3. TAF1 pre-mRNA elements identified in this study are independently targeted by developmental signaling pathways to result in tissue-specific inclusion of exon 12a and/or 13a. PMID: 18596254
Subcellular Location
Nucleus.
Protein Families
TAF1 family
Database Links

KEGG: dme:Dmel_CG17603

STRING: 7227.FBpp0293442

UniGene: Dm.7380

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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