tant Antibody

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Code	CSB-PA837397XA01DLU
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Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) tant Polyclonal antibody

Uniprot No.

Q8T0D4

Target Names

tant

Alternative Names

tant antibody; tan antibody; CG6586 antibody; Protein tantalus antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) tant protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Potential cofactor involved in sensory organ development. Despite its interaction with the Polycomb group protein Asx, it does not regulate the expression of homeotic genes.

Gene References into Functions

In contrast to NBAD-synthase, Tan is expressed constitutively in epidermis and does not respond directly to microbial challenge. The study shows the novel localization of tan in embryo central neural system and in different regions of adult brain. PMID: 21571070
The previously observed ability of TAN to move between the cytoplasm and nucleus, and to associate with DNA, provides a potential mechanism for TAN to respond to N signalling. PMID: 15717204
Tan expression is confined to the photoreceptor cells R1-R8. PMID: 17154266
Hybridization tests using D. melanogaster deficiencies that include tan show no evidence that this locus is involved in the lighter pigmentation of D. santomea females; rather, the pigmentation difference appears to involve at least 4 other loci. PMID: 20005810

Subcellular Location

Nucleus. Cytoplasm. Chromosome. Note=In embryos, it is predominantly cytoplasmic. In third instar larvae, it is predominantly nuclear or cytoplasmic depending on tissues. Colocalizes with Asx on many binding sites on polytene chromosomes, but does not bind to homeotic genes loci.

Tissue Specificity

Ubiquitously expressed in precellularized embryos. Then it decreases at cellular blastoderm to increase again during germ band extension. During germ band extension, it is highly expressed in somatic and visceral mesoderm. Ubiquitously expressed in imagin

Database Links

KEGG: dme:Dmel_CG6586

STRING: 7227.FBpp0305582

UniGene: Dm.1447

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tant Antibody

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Target Background