Recombinant Drosophila melanogaster Protein tantalus (tan)

Code CSB-YP837397DLU
MSDS
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Source Yeast
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Code CSB-EP837397DLU
MSDS
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Source E.coli
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Code CSB-EP837397DLU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP837397DLU
MSDS
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Source Baculovirus
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Code CSB-MP837397DLU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
tant
Uniprot No.
Alternative Names
tant; tan; CG6586; Protein tantalus
Species
Drosophila melanogaster (Fruit fly)
Expression Region
1-299
Target Protein Sequence
MDNIVYDFAK ITFQAKDNRS PTTNSNLSWQ LNQMALSDME EMQDTSEPIA PPESDDNVSS ESHDSDDVDS QLSRCEDNDD DSDCISGSSR RSSTFGARAG VARRRMPARV SKDNFNRICS AIMKPIKKKQ RKELNTNAQT LKSIEKIYTS RRMKKFTPTN LETIFEEPSD ENAADAEDDS EECSISSQVK VVKVWGRKLR RAISFSDGLN KNKILSKRRR QKVKKTFGKR FALKKISMTE FHDRLNKSFD SAMLEGDDAE AGGSAEAVNI PKTSMTMEDI QLPTMSSQHQ FLMQPAGFE
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Potential cofactor involved in sensory organ development. Despite its interaction with the Polycomb group protein Asx, it does not regulate the expression of homeotic genes.
Gene References into Functions
  1. In contrast to NBAD-synthase, Tan is expressed constitutively in epidermis and does not respond directly to microbial challenge. The study shows the novel localization of tan in embryo central neural system and in different regions of adult brain. PMID: 21571070
  2. The previously observed ability of TAN to move between the cytoplasm and nucleus, and to associate with DNA, provides a potential mechanism for TAN to respond to N signalling. PMID: 15717204
  3. Tan expression is confined to the photoreceptor cells R1-R8. PMID: 17154266
  4. Hybridization tests using D. melanogaster deficiencies that include tan show no evidence that this locus is involved in the lighter pigmentation of D. santomea females; rather, the pigmentation difference appears to involve at least 4 other loci. PMID: 20005810
Subcellular Location
Nucleus. Cytoplasm. Chromosome. Note=In embryos, it is predominantly cytoplasmic. In third instar larvae, it is predominantly nuclear or cytoplasmic depending on tissues. Colocalizes with Asx on many binding sites on polytene chromosomes, but does not bind to homeotic genes loci.
Tissue Specificity
Ubiquitously expressed in precellularized embryos. Then it decreases at cellular blastoderm to increase again during germ band extension. During germ band extension, it is highly expressed in somatic and visceral mesoderm. Ubiquitously expressed in imagin
Database Links

KEGG: dme:Dmel_CG6586

STRING: 7227.FBpp0305582

UniGene: Dm.1447

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