tbg-1 Antibody

Code CSB-PA333900XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans tbg-1 Polyclonal antibody
Uniprot No.
Target Names
tbg-1
Alternative Names
tbg-1 antibody; F58A4.8 antibody; Tubulin gamma chain antibody; Gamma-tubulin antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans tbg-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
Gene References into Functions
  1. These results show that NOCA-1 acts with gamma-tubulin to assemble non-centrosomal arrays in multiple tissues and highlight functional overlap between the ninein and Patronin protein families. PMID: 26371552
  2. Data show expression of tbg-1 during the development revealed differential expression in different developmental stages and that gamma-tubulin expression was observed through out the development from embryonic and post-embryonic stages. PMID: 17160625
  3. Gamma-tubulin in the PCM stabilizes the nascent daughter centriole by promoting microtubule addition to its outer wall. Such a mechanism may help restrict new centriole assembly to the vicinity of preexisting parent centrioles that recruit PCM. PMID: 18299348
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell junction, hemidesmosome. Cell junction, adherens junction.
Protein Families
Tubulin family
Database Links

KEGG: cel:CELE_F58A4.8

STRING: 6239.F58A4.8.2

UniGene: Cel.19457

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