SUA7 Antibody

Code CSB-PA010001XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SUA7 Polyclonal antibody
Uniprot No.
Target Names
SUA7
Alternative Names
SUA7 antibody; YPR086W antibody; P9513.4 antibody; Transcription initiation factor IIB antibody; General transcription factor TFIIB antibody; Transcription factor E antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SUA7 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
Gene References into Functions
  1. crystal structure of RNA polymerase II-TFIIB complex at 3.8 A resolution revealing carboxyl-terminal region of TFIIB, located above polymerase active center cleft but showing none of B finger; linker between amino- & carboxyl-terminal regions also seen PMID: 19965383
  2. Results describe the architecture of transcription factor IIB and the the RNA polymerase II transcription preinitiation complex (PIC). PMID: 15479635
  3. TBP1(E186D) temperature-sensitivity and slow-growth phenotypes might have been caused by insufficient amounts of Tbp1p for efficient transcription of the rRNA genes by RNA polymerase I PMID: 17680779
  4. TFIIB binds RNA Polymerase II at the terminator, which in turn associates with the promoter scaffold giving TFIIB a role in gene looping. PMID: 17803944
  5. the crystal structure of the complete RNA polymerase II - transcription factor IIB complex at 4.3 A resolution PMID: 19820686

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Subcellular Location
Nucleus.
Protein Families
TFIIB family
Database Links

KEGG: sce:YPR086W

STRING: 4932.YPR086W

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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