TMED5 Antibody

Code CSB-PA023661XA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TMED5 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
CGI 100 antibody; DKFZp781B2248 antibody; p24 family protein gamma-2 antibody; p24gamma2 antibody; p28 antibody; RP5 976O13.2 antibody; TMED 5 antibody; TMED5 antibody; TMED5_HUMAN antibody; Transmembrane emp24 domain containing protein 5 antibody; Transmembrane emp24 domain-containing protein 5 antibody; Transmembrane emp24 protein transport domain containing 5 antibody; UNQ397/PRO733 antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens (Human)
Immunogen
Recombinant Homo sapiens (Human) TMED5 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport.
Gene References into Functions
  1. The luminal alpha-helical but not GOLD domain of p24gamma2 was required for efficient GPI-AP transport. PMID: 24778190
  2. Expression of cgi-100 mRNA decreased in a dose- and time-dependent manner in the K562 cells treated with matrine and over-expression of cgi-100 elevates the proliferation and the immaturity level of K562 cells. PMID: 18549622
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Note=Probably cycles between compartments of the early secretatory pathway.
Protein Families
EMP24/GP25L family
Database Links

HGNC: 24251

OMIM: 616876

KEGG: hsa:50999

STRING: 9606.ENSP00000359305

UniGene: Hs.482873

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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