Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) TMM Polyclonal antibody

Uniprot No.

Q9SSD1

Target Names

TMM

Alternative Names

TMM; RLP17; At1g80080; F18B13.16; Protein TOO MANY MOUTHS; Receptor-like protein 17; AtRLP17

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana TMM protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Target Background

Function

Promotes cell fate progression in stomatal development. In leaves, needed to correctly orient spacing divisions, to limit the number of asymmetric divisions in neighbor cells, and to promote the asymmetric (amplifying) divisions of meristemoids. In stems, promotes the conversion of meristemoids into guard mother cells (GMC). Positively regulates CAPRICE (CPC) expression in differentiating stomaless-forming cell files. Forms constitutive complexes with ERECTA and ERL1 involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN. Modulates the activity of the ligand-receptor pairs EPF2-ERECTA and EPF1-ERL1 in stomatal development. Functions in a combinatorial specific manner with the ERECTA-family (ERf) receptor kinases in the regulation of the immune response.

Gene References into Functions

Data demonstrate that TMM dictates the specificity of ERECTA family for the perception of different epidermal patterning factor peptides (EPfs), thus functioning as a specificity switch for the regulation of the activities of ERfs. PMID: 28536146
Brassinosteroid organ-specific effects on stomatal production might coordinate with the TMM organ-specific actions. PMID: 25234048
TMM was involved in Abscisic Acid (ABA) signaling transduction. Overexpression of TMM resulted in the reduction of leaf trichomes and their branches. PMID: 24553751
CHAL and the EPFs both act through ER family receptors to repress stomatal production, but are subject to opposite regulation by TMM PMID: 20056678
TMM interacts with other proteins to modulate precursor cell fate and progression in an organ and domain-specific manner. PMID: 18979118

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Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Families

RLP family

Tissue Specificity

In epidermal cells of developing shoots and leaves, but not in roots. Expressed in the stomatal cell lineage in the developing epidermis. Accumulates strongly in meristemoid mother cells (MMC) and meristemoids, somewhat less in meristemoid sister cells (s

Database Links

KEGG: ath:AT1G80080

STRING: 3702.AT1G80080.1

UniGene: At.33989

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TMM Antibody

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