twi Antibody

1. The level of Twi activity determines whether the cellular events of ventral furrow formation, epithelial-to-mesenchymal transition, cell division and mesodermal migration occur. PMID: 24915423
2. Our studies identify Akirin as a nuclear factor that genetically interacts with the BRM complex and is required for optimal expression of the Twist-dependent Dmef2 enhancer PMID: 22396663
3. conclude that Twi is an essential Notch co-regulator in myogenic progenitor cells and has the potential to confer specificity on Notch signalling at over 170 genes, showing that a single factor can have a profound effect on the output of the pathway. PMID: 20610485
4. The role of Twist in the Toll/Dorsal signaling pathway that specifies patterning thresholds of gene expression PMID: 12091311
5. anterior-gut formation is mechanically induced by the movement of germ-band extension through the induction of Twist expression in stomodeal cells PMID: 12932320
6. High Twist levels direct cells to the body wall muscle fate, whereas low levels are permissive for gut muscle and fat body fate. PMID: 15128668
7. twi expression in Drosophila during gastrulation and mesoderm formation was compared to twi expression in the same embryonic development stages in Tribolium castaneum. PMID: 15645317
8. Twist binds to almost all mesodermal cis-regulatory modules to provide the competence to integrate inputs from more specialized transcription factors. PMID: 17322403
9. These experiments show that mechanically induced Twist upregulation in stomodeal cells is necessary for subsequent midgut differentiation in Drosophila embryos. PMID: 18804441
10. Data show that cell fate decisions in the dorsal and lateral Twi- and Tin-positive mesoderm of Drosophila melanogaster depend on the antagonistic action of the transcription factor Lame duck and the zinc finger homeodomain factor Zfh1. PMID: 19028484

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KEGG: dme:Dmel_CG2956

STRING: 7227.FBpp0071864

UniGene: Dm.5605