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RO60 Antibody

Datasheet
Code CSB-PA025071ZA01MO
Size
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) RO60 Polyclonal antibody
Uniprot No.
O08848
Target Names
RO60
Alternative Names
60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2), Trove2, Ssa2
Raised in
Rabbit
Species Reactivity
Mus musculus
Immunogen
Recombinant Mus musculus RO60 protein
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugate
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Related Products

RO60 Proteins

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Target Background

Function
RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation.; May play roles in cilia formation and/or maintenance.
Gene References into Functions
  1. These data support the hypothesis that antibodies to Ro274 deposit in salivary glands can enter intact salivary gland cells and are involved in the dysregulation of salivary flow in SS. PMID: 25370295
  2. Restricted specificity of intermolecular spreading to endogenous La (SS-B) and 60 kDa Ro (SS-A) in experimental autoimmunity. PMID: 12121436
  3. differences in the epitope spreading after 60 kDa Ro peptide immunization in several strains of mice PMID: 12410797
  4. Ro protein has a role in preventing an autoimmune syndrome characterized by anti-ribosome antibodies, anti-chromatin antibodies, and glomerulonephritis PMID: 12788971
Subcellular Location
Cytoplasm.
Protein Families
Ro 60 kDa family
Tissue Specificity
Highest in brain, followed by lung, muscle, kidney and heart. Lower levels are found in testis, liver and spleen.
Database Links
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