RO60

RO60 is also known as SS - A/Ro60, and its full name is 60 kDa Ro ribonucleoprotein. This protein is a key component of the Ro ribonucleoprotein complex. It binds to specific non - coding RNAs and plays crucial roles in RNA metabolism and quality control. In the cell, it participates in the Toll - like receptor signaling pathway, which is important for immune responses.
Abnormalities of RO60 are associated with autoimmune diseases such as Sjögren's syndrome and systemic lupus erythematosus. Regarding drug development, targeting RO60 is still in the early research stage. Scientists aim to develop drugs that can modulate its function to treat related autoimmune disorders.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TROVE2 Antibody (CSB-PA13749A0Rb)

Validated Data

Western blot
All lanes: TROVE2 antibody at 2µg/ml
Lane 1: Hela whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 61, 24, 59, 60 kDa
Observed band size: 61 kDa

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA13749A0Rb at dilution of 1:20

Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA13749A0Rb at dilution of 1:20

Western Blot
Positive WB detected in: MCF-7 whole cell lysate, Hela whole cell lysate, PC-3 whole cell lysate, Mouse heart tissue, Mouse spleen tissue, Mouse lung tissue
All lanes: TROVE2 antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 61, 24, 59, 60 kDa
Observed band size: 61 kDa

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA13749A0Rb at dilution of 1:100

Immunofluorescent analysis of A549 cells using CSB-PA13749A0Rb at dilution of 1:100

Western Blot
Positive WB detected in: Hela whole cell lysate, Rat kidney tissue
All lanes: TROVE2 antibody at 3.4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 61, 24, 59, 60 kDa
Observed band size: 61 kDa

Immunofluorescent analysis of PC-3 cells using CSB-PA13749A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA13749A0Rb at dilution of 1:100

The following RO60 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

RO60 Antibodies

RO60 Proteins

RO60 Antibodies

RO60 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA025071GA01HU	TROVE2 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA13749A0Rb	TROVE2 Antibody	Human, Mouse, Rat	ELISA, WB, IHC, IF
CSB-PA13749D0Rb	TROVE2 Antibody, Biotin conjugated	Human	ELISA
CSB-PA050155	TROVE2 Antibody	Human	WB, ELISA

RO60 Proteins

RO60 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP025071HU CSB-EP025071HU CSB-BP025071HU CSB-MP025071HU CSB-EP025071HU-B	Recombinant Human RNA-binding protein RO60 (RO60)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP025071HU1	Recombinant Human RNA-binding protein RO60 (RO60), partial	E.coli

Promotions

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

Apoptosis mediated by mitochondria The Overview of Hippo Signaling Pathway The Overview of Autophagy Crosstalk Between Autophagy and Apoptosis The Overview of Wnt Signaling Pathway The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic Targets The overview of TGF-β signaling pathway PI3K-Akt Signaling Pathway and Cancer Apoptosis mediated by endoplasmic reticulum Apoptosisi mediated by death receptor Aesthetic Appreciation of Apoptosis Signal Pathway An Overview of Cell Death: Necrosis and Apoptosis Do You Really Know TGF-β Superfamily? Double-Edged Sword: TGF-β The Overview of PI3-Alt Signaling Pathway How to Inquire and Utilize the Signal Pathway on KEGG LPS/TLR4 Signal Transduction Pathway Epigenetic Histone Modifications Pathway What A Paradoxical TNF Signaling Pathway-Based on Different Receptors The Overview of Fc Receptors- Classification, Related Signaling Pathways and Application

RO60

Popular Product: