UBE2K Antibody

Code CSB-PA025460XA01BO
Size Pls inquire
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Product Details

Full Product Name Rabbit anti-Bos taurus (Bovine) UBE2K Polyclonal antibody
Uniprot No. P61085
Target Names UBE2K
Alternative Names UBE2K antibody; HIP2Ubiquitin-conjugating enzyme E2 K antibody; EC 2.3.2.23 antibody; E2 ubiquitin-conjugating enzyme K antibody; Huntingtin-interacting protein 2 antibody; HIP-2 antibody; Ubiquitin carrier protein antibody; Ubiquitin-conjugating enzyme E2-25 kDa antibody; Ubiquitin-conjugating enzyme E2(25K) antibody; Ubiquitin-conjugating enzyme E2-25K antibody; Ubiquitin-protein ligase antibody
Raised in Rabbit
Species Reactivity Bos taurus (Bovine)
Immunogen Recombinant Bos taurus (Bovine) UBE2K protein
Immunogen Species Bos taurus (Bovine)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

Function
(From Uniprot)
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B; in vitro supports ubiquitination of NFKB1.
Subcellular Location Cytoplasm.
Protein Families Ubiquitin-conjugating enzyme family
Database Links

KEGG: bta:281225

STRING: 9913.ENSBTAP00000026871

UniGene: Bt.65293

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