UBE2K Antibody

Datasheet

Code	CSB-PA025460XA01BO
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Target Background

Product Details

Full Product Name

Rabbit anti-Bos taurus (Bovine) UBE2K Polyclonal antibody

Uniprot No.

P61085

Target Names

UBE2K

Alternative Names

UBE2K antibody; HIP2Ubiquitin-conjugating enzyme E2 K antibody; EC 2.3.2.23 antibody; E2 ubiquitin-conjugating enzyme K antibody; Huntingtin-interacting protein 2 antibody; HIP-2 antibody; Ubiquitin carrier protein antibody; Ubiquitin-conjugating enzyme E2-25 kDa antibody; Ubiquitin-conjugating enzyme E2(25K) antibody; Ubiquitin-conjugating enzyme E2-25K antibody; Ubiquitin-protein ligase antibody

Raised in

Rabbit

Species Reactivity

Bos taurus (Bovine)

Immunogen

Recombinant Bos taurus (Bovine) UBE2K protein

Immunogen Species

Bos taurus (Bovine)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B; in vitro supports ubiquitination of NFKB1.

Subcellular Location

Cytoplasm.

Protein Families

Ubiquitin-conjugating enzyme family

Database Links

KEGG: bta:281225

STRING: 9913.ENSBTAP00000026871

UniGene: Bt.65293

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Ubiquitin mediated proteolysis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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UBE2K Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background