UBP13 Antibody

Code CSB-PA802935XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) UBP13 Polyclonal antibody
Uniprot No.
Target Names
UBP13
Alternative Names
UBP13 antibody; At3g11910 antibody; F26K24.20 antibody; MEC18.1 antibody; Ubiquitin carboxyl-terminal hydrolase 13 antibody; EC 3.4.19.12 antibody; Deubiquitinating enzyme 13 antibody; AtUBP13 antibody; Ubiquitin thioesterase 13 antibody; Ubiquitin-specific-processing protease 13 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana UBP13 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Positive regulator of root meristem development that, together with UBP12, prevents the ubiquitination and turnover of RGFR1 induced by the RGF1 hormone peptide, thus influencing PLT1 and PLT2 expression.
Gene References into Functions
  1. UBP12/13 are regulators of the RGF1-RGFR1-PLT1/2 signaling pathway and UBP12/13 can counteract RGF1-induced RGFR1 ubiquitination, stabilize RGFR1, and maintain root cell sensitivity to RGF1 PMID: 29339500
  2. UBP12 and UBP13 belong to an ancient gene family and represent plant homologues of metazoan USP7. Drosophila USP7 shares a function in heterochromatic gene repression with UBP12/13 and their homologue UBP26. In summary, USP7-like proteins are essential for gene silencing in diverse genomic contexts. PMID: 27525512
  3. The Deubiquitinating Enzymes UBP12 and UBP13 Positively Regulate MYC2 Levels in Jasmonate Responses PMID: 28536144
  4. UBP12 and UBP13 proteins play important role in the control of the circadian clock and photoperiodic flowering. PMID: 23645632
  5. AtUBP13 is a deubiquitinating enzyme capable of cleaving lysine-48-linked ubiquitin chains. PMID: 21388379

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Protein Families
Peptidase C19 family
Database Links

KEGG: ath:AT3G11910

STRING: 3702.AT3G11910.1

UniGene: At.25337

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