UFD2 Antibody

Code CSB-PA862086XA01SXV
Product Type Polyclonal Antibody
Uniprot No. Q9HE05
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) UFD2 protein
Raised in Rabbit
Species Reactivity Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Ubiquitin conjugation factor E4 (EC 6.3.2.-) (Ubiquitin fusion degradation protein 2) (UB fusion protein 2) ufd2 SPAC145.04 SPAC20H4.10
Immunogen Species Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Gene Names ufd2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function E4 ubiquitin chain-elongation enzyme specifically involved in polyubiquitin chain assembly. Binds to cdc48 and elongates mono- and diubiquitinated ERAD substrates presented by the ufd1-npl4-cdc48 (UNC) AAA ATPase complex to a chain length of 4 to 6 ubiquitin moieties. Delivers these polyubiquitinated substrates to downstream ERAD components, which target them to the proteasome. Enhances ubiquitination at 'Lys-48', but not at 'Lys-29' of the Ub moiety.
Subcellular Location Cytoplasm, Nucleus
Protein Families Ubiquitin conjugation factor E4 family
Database Links

KEGG: spo:SPAC20H4.10

STRING: 4896.SPAC20H4.10.1

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