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| Code | CSB-PA960259XA01SVG |
| Size | US$299 |
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The generation of the VAM6 polyclonal antibody commences with the selection of a recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) VAM6 protein as the immunogen. This protein is employed to immunize a rabbit, inducing an antibody response. Subsequently, serum is collected from the rabbit to obtain polyclonal antibodies. These antibodies are then purified through protein A/G affinity chromatography. The VAM6 antibody's functional utility is assessed in ELISA and WB assays, confirming its efficacy in detecting Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) VAM6 protein.
The Saccharomyces cerevisiae VAM6 protein mainly regulates membrane fusion events in the endosomal and vacuolar pathways. It is involved in the fusion of vesicles with the vacuole, a membrane-bound organelle in yeast cells that functions in protein degradation, storage, and recycling. The VAM6 protein plays a crucial role in maintaining the integrity and functionality of the vacuole by ensuring proper delivery of cargo molecules and vesicles to their designated compartments.
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KEGG: sce:YDL077C
STRING: 4932.YDL077C
