VPS74 Antibody

Datasheet
Code CSB-PA521111XA01SXV
Product Type Polyclonal Antibody
Uniprot No. O14205
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) VPS74 protein
Raised in Rabbit
Species Reactivity Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Vacuolar protein sorting-associated protein 74 vps74 SPAC5D6.13 SPAPJ735.02c
Immunogen Species Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Gene Names vps74
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains. Involved in vacuolar protein sorting (By similarity).
Subcellular Location Golgi apparatus, Golgi stack membrane, Peripheral membrane protein, Cytoplasmic side
Protein Families GOLPH3/VPS74 family
Database Links

KEGG: spo:SPAC5D6.13

STRING: 4896.SPAC5D6.13.1

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