WAT1 Antibody

Datasheet
Code CSB-PA529159XA01SXV
Product Type Polyclonal Antibody
Uniprot No. O74184
Delivery Make-to-order
Immunogen Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) WAT1 protein
Raised in Rabbit
Species Reactivity Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugate
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Target of rapamycin complex subunit wat1 (TORC subunit wat1) (WD repeat-containing protein pop3) pop3 wat1 SPBC21B10.05c
Immunogen Species Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Protocols ELISA Protocol
Gene Names pop3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function component of both TORC1 and TORC2, which regulate multiple cellular processes to control cell growth in response to environmental signals. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls cell growth and ribosome biogenesis by regulating ribosomal protein gene expression. TORC1 negatively controls G1 cell-cycle arrest, sexual development and amino acid uptake. Represses mating, meiosis and sporulation efficiency by interfering with the functions of the transcription factor ste11 and the meiosis-promoting RNA-binding protein mei2. TORC2 is required for cell survival under various stress conditions. TORC2 positively controls G1 cell-cycle arrest, sexual development and amino acid uptake. Positively regulates amino acid uptake through the control of expression of amino acid permeases
Subcellular Location Cytoplasm, Nucleus
Protein Families WD repeat LST8 family
Database Links

KEGG: spo:SPBC21B10.05c

STRING: 4896.SPBC21B10.05c.1

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